Start main page content

Clinical HIV Research Unit (CHRU)

Unit Director: Professor Ian Sanne

The Clinical HIV Research Unit (CHRU), an internationally recognised research and technical assistance unit delivers excellence and quality clinical, epidemiologic and health economic research services in Johannesburg and ensures that this information is invested at operational level for the prevention, treatment and management of HIV and associated diseases.

Located at the Themba Lethu Clinic (TLC), HJH, it is one of the largest HIV and TB clinics in South Africa. The CHRU epidemiology division operates independentlyunder HE2RO located in Parktown.

The Health Economics and Epidemiology Research Office (HE²RO) is a division of the Wits Health Consortium (WHC) of Wits. It conducts applied, policy- and program-relevant research and evaluation on issues of public health importance in South Africa. HE²RO was established in 2004 as a collaboration between WHC and the Center for Global Health and Development at Boston University in the United States.

It focuses on understanding the economic andepidemiological consequences of the HIV and TB epidemics and the effectiveness, benefits, and costsof interventions. It responds directly to requests for information and technical assistance from the National Department of Health, National Health Laboratory Service (NHLS), provincial departments of health, PEPFAR partners, and healthcare providers, answering questions of immediate practical relevance to these stakeholders.

The CHRU’s research focus is HIV treatment in adults, HIV prevention, Tuberculosis (TB), Cervical Cancer and HIV related Malignancies such as Karposi Sarcoma has made significant contributions to these research disciplines, with over 250 publications since its inception in 1999. CHRU, in collaboration with Right to Care, offers an unique third line clinic to diagnose and treat third line patients. CHRU has completed over 66 antiretroviral therapy (ART) studies in phase I-III research. It was the first International AIDS Clinical Trials Group (ACTG) Site in 2002, and has since been one of the highest performing ACTG international site. CHRU implemented five new studies in 2014 and eleven in 2015


Pap-smear Services

Community Advisory Board (CAB) CHRU staff

At CHRU it is our mission to deliver excellence and quality in clinical, epidemiologic and health economic research, services and support in Johannesburg, and to further ensure that this information is invested atoperational level for the prevention, treatment and management of HIV and associated diseases.