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Cardiovascular Pathophysiology and Genomics Research Unit

The Cardiovascular Pathophysiology and Genomic Research Unit (CPGRU) is a University recognised unit in the School of Physiology with extensive collaborations across clinical departments. Each year the unit contributes to on average 25-30 papers and graduates several MSc and PhD students. Several of the unit’s members carry substantial international recognition for their work. The unit’s members are interested in the mechanisms of cardiovascular disease with the goal of identifying novel approaches to preventing or managing cardiovascular events. The unit has special interests in the impact on the cardiovascular system of aortic dysfunction, hypertension, diabetes mellitus, obesity, chronic inflammation (rheumatoid arthritis), and HIV. In addition, the unit contributes to the understanding of heart failure and sex-differences in cardiovascular disease. The unit is unique in the world today in that it incorporates both basic science and clinical approaches to answering fundamental questions on the mechanisms of cardiovascular disease.