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AWI-Gen Study: Cardiometabolic disease (CMD) research

The AWI-Gen Collaborative Centre (AWI-Gen) is a Human Heredity and Health in Africa (H3A) Consortium study. It is a partnership between Wits University and the International Network for the Demographic Evaluation of Populations and their Health in low and middle income countries (INDEPTH).  This NIH-funded Human Heredity and Health in Africa (H3Africa) study aims to examine genomic and environmental factors that influence body composition, body fat distribution and cardiometabolic disease risk in middle aged African populations. For more information visit. This research project is headed by Professor Michele Ramsay at SBIMB. 


Map showing locations of catchment areas for AWI-Gen study in Africa

AWI-Gen  Participating Research Centres


The AWI-Gen resource is explained in the link:

The AWI-Gen project addresses three broad themes:

  • Capacity development to enhance capability for genomic research in Africa in order to address critical problems of health and disease;
  • Understanding the genomic architecture of sub-Saharan African populations and its impact on disease susceptibility; and
  • Identifying the genetic, genomic and environmental risk factors for obesity by leveraging off existing longitudinal cohorts and adding a genomic dimension to this research.

Link to recent resource paper: