WADDP: Open for Innovation Our research is translational and focused on advancing technologies in Drug Delivery, Nanomedicine, Tissue Engineering, Regenerative Medicine, 3D-Bioprinting and Bio-Inspired Systems of the future.
WADDP: Open for Innovation Our research is translational and focused on advancing technologies in Drug Delivery, Nanomedicine, Tissue Engineering, Regenerative Medicine, 3D-Bioprinting and Bio-Inspired Systems of the future.
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Our Research

World-Class > Collaborative > Responsive > Innovative > Impactful > Saving Lives

The WADDP is a team of highly passionate and skilled Pharmaceutical Scientists led by Professor Yahya Choonara innovating 21st century patient-centric Drug (or other Bioactive) Delivery Systems either as standalone prototypes or interfaced with Nanomedicine, Tissue Engineering, Regenerative Medicine and supported by using Functional Biomaterials to design world leading pharmaceutical therapies. The team is obsessed with:

Answering Big Questions: High impact, unmet therapeutic needs, contextually relevant, globally applicable

Societal Relevance: Design safe, effective and cost-sensitive patient centric products

Critical Mass: Collaborative innovation, world-class labs, responsive and skilled pharmaceutical researchers 

Sustainability: Translational pharmaceutical sciences research

As the pathophysiology of infectious, lifestyle and hereditary diseases become clearer, the need for more targeted and personalized therapies become vital to improve the quality of life of patients.

Research at the WADDP plays an integral role in meeting this need through collaborative engagement with with expert Clinicians and other scientists focused on optimizing the health and wellness of patients. The team is highly regarded for producing first-in-the-world technologies in the following Thematic Areas:

  • Ultra-Fast Oral Dissolving Matrices
  • Targeted Nanosystems for Infectious Diseases
  • Nanomedicine and Nanovector Technologies
  • NeuroPharmaceutical Devices
  • Interventions for Neural Tissue Regeneration
  • Targeted Cancer Therapies
  • Ocular Inserts for Bioactive Delivery
  • Oral Delivery of Proteins and Peptides
  • Targeted Anti-Thrombolytic Systems
  • Advanced Wound Healing Platforms
  • Chronotherapeutic Technologies
  • Gastroretentive Systems for NAW Molecules
  • Theranostics and ElectroActive Systems 
  • 3D-BioPrinting of Biomimetic Scaffolds
  • Stimuli-Responsive Biomaterials
  • Probiotics and Nutraceuticals
  • PharMATHaceutics Optimization  
  • Pharmaceutical Reformulation

Below are a selection of published projects under the WADDP Thematic Areas:

  • Repair and regeneration of the injured spinal cord using 3D neuro-injectable scaffolds/hydrogels
  • Targeted therapies in ovarian and cervical cancer using antibody-functionalized nanosystems
  • Ocular devices for anterior/posterior segment disease using ocular-terials, geo-solid drops
  • Nano-co-Plexes for magnetic intranasal delivery of carmustine for targeted treatment of glioma
  • 3D-BioPrinted geo-scaffolds for spatial control of cell differentiation using self-assembled bioinks
  • First in-the-world chelating nanosystems as intracranial implants for neurodegenerative diseases
  • Intra-arterial sensory devices to monitor and treat high blood factors in chronic lifestyle diseases
  • Stimuli-responsive oral ghost matrices and core-melt tablets to deliver proteins/peptides orally
  • Pioneered PEiGOR to describe jump diffusion in electro-active hydrogels for neuropathic pain
  • First-in-the-world stimuli-active matrices for spaced-defined drug release in ulcerative colitis
  • The first-ever MRI analysis of hydration dynamics in oral layered tablets using in silico modeling
  • Intravaginal devices to reduce and prevent STI/HIV transmission using VagiTab technology
  • In situ forming nanogels with neuroblasts or mature neurons for treating neurodegeneration
  • Functionalized carbon nanotubes for targeted treatment of stroke using novel aptamer technology
  • Nano-reinforced cryogel scaffolds for neural tissue regeneration using 3D-Bioprinted models
  • Neuro-replacement therapy in traumatic brain injury using a 3D-BioPrinted neuro-mimicry system
  • Arresting CS-proteoglycans progression in ovarian cancer using X-linked extracellular nanosystem
  • Thixotropic synovial bio-fluid for orthopaedic insertion using polysaccharide infused glucosamine
  • 3D-BioPrinted biofilms for burn and diabetic foot wound healing as a bio-inspired pseudo-skin
  • Synthesis of redox-active drugs to treat TB and malaria based on clofazimine redox chemistry
 
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