Why study Biopharmaceutics and Clinical Pharmacokinetics?
The manner in which a drug is taken is called a dosage regimen. Both the duration of drug therapy and the dosage regimen depend on the therapeutic objectives, which may be either to cure the mitigation, or the prevention of the disease. Because all drugs exhibit undesirable effects such as drowsiness, dryness of the mouth, nausea, GIT irritation, etc., successful drug therapy is obtained by carefully balancing the desirable and undesirable effects. To achieve optimal therapy;
(1) The appropriate "drug of choice" must be selected.
(2) How often the drug is too be administered must be decided.
(3) How much of the drug must be administered must be determined.
(4) For how long must the drug therapy be maintained must be decided.
In practice, these questions cannot be divorced from each other. For example, the convenience of giving a bigger dose less frequently may be more than offset by an increased incidence of toxicity.